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Dr Li Xiuyuan
PolyU Scholars Hub

Dr Li Xiuyuan, Ted

Assistant Professor

Research Interests

  • Neuroscience
  • synaptic plasticity
  • protein engineering
  • rational biosensor design

Achievements

  1. Lin D*, Li X*, Park PJ, Tang B, Shen H, Grimm JB, Falco N, Baker D, Lavis LD, and Cohen AE, “Time-tagged ticker tapes for intracellular recordings” Nat. Biotechnol., 2023, (* contributed equally).
  2. Cogan D*, Zhang K*, Li X, Li S, Pintilie G, Roh SH, Craik CS, Chiu W, and Khosla C, “Mapping the catalytic conformations of an assembly-line polyketide synthase module” Science, 2021, 374 (6568), 729–734 (* contributed equally).
  3. Cogan D, Li X, Sevillano N, Mathews I, Matsui T, Cane DE, Craik CS and Khosla C, “Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction” J. Am. Chem. Soc., 2020, 142 (35), 14933–14939.
  4. Li X, Sevillano N, La Greca F, Hsu J, Mathews I, Matsui T, Craik CS and Khosla C, “Discovery and Characterization of a Thioesterase-Specific Monoclonal Antibody That Recognizes the 6-Deoxyerythronolide B Synthase” Biochemistry, 2018, 57 (43), 6201–6208.
  5. Li X, Sevillano N, La Greca F, Deis L, Liu Y, Deller M, Mathews I, Matsui T, Cane DE, Craik CS and Khosla C, “Structure-Function Analysis of the Extended Conformation of a Polyketide Synthase Module” J. Am. Chem. Soc., 2018, 140 (21), 6518–6521.
  6. Lowry B*, Li X*, Robbins T*, Cane DE and Khosla C, “A Turnstile Mechanism for the Controlled Growth of Biosynthetic Intermediates on Assembly Line Polyketide Synthases”, ACS Cent. Sci. 2016, 2 (1), 14–20 (* contributed equally).
  7. Simon MD, Heider PL, Adamo A, Vinogradov AA, Mong SK, Li X, Berger T, Policarpo RL, Zhang C, Zou Y, Liao X, Spokoyny AM, Jensen KF and Pentelute BL, “A Rapid Flow-Based Peptide Synthesis” Chembiochem., 2014, 15 (5), 713-20.
  8. Wang W, Wang S, Li X, Collin J-P, Liu J and Lin N, “Probing Electronic Super Exchange Coupling at Isolated Poly-p-phenylene Molecules” J. Am. Chem. Soc., 2010, 132 (25), 8774–8778.

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