- Y824-03
- +852 3400 8881
- man-yuen.lee@polyu.edu.hk
ORCID ID
SCOPUS IDEducation and Academic Qualifications
- Bachelor of Science in Applied Biology with Biotechnology, The Hong Kong Polytechnic University
- Master of Philosophy, The Chinese University of Hong Kong
- Doctor of Philosophy, The Chinese University of Hong Kong
Research Overview
My research focuses on (1) development of drugs for prevention and treatment of obesity-related metabolic disorders and cancer, and aging-related diseases; (2) development of in utero therapeutic interventions to combat against the adverse effects of maternal diabetes and obesity on fetal development.
Research Interests
Achievements
- . Lee LMY, Tam STK, McCaffery PJ and Shum ASW (2019). Highly sensitive quantitative determination of retinoic acid levels, retinoic acid synthesis, and catabolism in embryonic tissue using a reporter cell-based method. In: Ray SK (eds) Retinoid and Rexinoid Signaling. Methods and Protocols. Methods in Molecular Biology vol 2019, p.181-192, Humana Press, New York
- . Lee LMY, Leung MBW, Kwok RCY, Leung YC, Wang CC, McCaffery PJ, Copp AJ and Shum ASW (2017). Perturbation of retinoid homeostasis increases malformation risk in embryos exposed to pregestational diabetes. Diabetes 66, 1041-1051.
- . Lee LMY, Leung CY, Tang WWC, Choi HL, Leung YC, McCaffery PJ, Wang CC, Woolf AS and Shum ASW (2012). A paradoxical teratogenic mechanism for retinoic acid. Proc Natl Acad Sci USA 109, 13668–13673.
- Methods for Inducing Intermittent Fasting and Modulating Autophagy (US Provisional Application for Patent No. 62/942,354. Filed on 2 Dec 2019)
