Prof. Xiangdong Li has recently been awarded RMB 15,000,000 from the NSFC Major Research Plan for a two-year (2021-2022) Integrated Project entitled “Joint toxicity mechanisms and contributions of key bioactive components in airborne fine particulate matters (PM2.5) from typical urban areas of China”.
In collaboration with the Research Center for Eco-Environmental Sciences of Chinese Academy of Sciences, Peking University, and Tongji University, Prof. Li will employ advanced approaches from computational toxicology to machine learning, live cell imaging, multi-omics, and genome editing to answer what key toxic constituents and their mixtures are responsible for health effects of PM2.5, and, more importantly, to provide scientific evidence and technical support for precise mitigation of high-risk bioactive components that is essential for China’s strategies in the low-to-medium PM2.5 pollution scenario in the future.