Research at FAST

Institute of Textiles & Clothing Institute of Textiles & Clothing 151 Qualification PhD (Cornell) ORCID ID 0000-0001-8850-2184 Dr JI Ying Research Assistant Professor Reserach Overview Biodegradable polymeric materials • Synthetic amino acid based poly(ester amide)s, polyesters with tunable enzymatic and hydrolytic degradation profile • Oxo-degradation and biodegradation of post-consumer polymeric materials Functional materials for biomedical applications • Synthesis and development of polymeric materials, including polyacrylates/methacrylates, cyclodextrin based polyrotaxane, biodegradable poly(ester amide)s, polyesters and natural polysaccharide derivatives (chitosan, hyaluronic acid, etc.) • Developing mesoporous silica nanoparticles with fine-tuning of morphological properties, physicochemical properties and lipid/polymer coating, etc. • Surface engineering of materials for biointerface modulation Representative Publications • Ying Ji , Xiangsheng Liu, Juan Li, Xiaodong Xie, Max Huang, Jinhong Jiang, Yu-Pei Liao, Timothy Donahue, Huan Meng. Use of ratiometrically designed nanocarrier targeting CDK4/6 and autophagy pathways for effective pancreatic cancer treatment. Nature Communications 11, no. 1 ( 2020 ): 1-15 • Ying Ji , Xiangsheng Liu, Max Huang, Melissa Spencer, Huan Meng. Development of self-assembled multi-arm polyrotaxanes nanocarriers for systemic plasmid delivery in vivo. Biomaterials 192( 2019 ), 416-428 • Ying Ji , Jihui Zhao, Shuo Shan, Chih-Chang Chu. Light- facilitated drug delivery system from pseudo-protein/ hyaluronic acid nanocomplex with improved anti-tumor effect. Nanoscale 11( 2019 ), 9987-10003 • Ying Ji , Jihui Zhao, Chih-Chang Chu. Enhanced MHC-I Antigen Presentation from the Delivery of Ovalbumin by Light-facilitated Biodegradable Poly (ester amide) s Nanoparticles. Journal of Materials Chemistry B, 6( 2018 ), 1930-1942 • Ying Ji , Shuo Shan, Mingyu He, Chih-Chang Chu. A novel pseudo-protein based biodegradable nano-micellar platform for the delivery of anti-cancer drug. Small 13( 2017 ), 1601491 • Ying Ji , Jihui Zhao, Chih-Chang Chu. Biodegradable nanocomplex from hyaluronic acid and arginine based poly(ester amide)s as the Delivery Vehicles for Photodynamic Therapy. Journal of Biomedical Materials Research Part A, 105( 2017 ), 1487-1499 • Ying Ji , Shan Shuo, Mingyu He, Chih-Chang Chu. Inclusion complex from cyclodextrin-grafted hyaluronic acid and pseudo-protein for the delivery of gambogic acid. Acta Biomaterialia 62( 2017 ), 234-245 • Ying Ji , Yu Wei, Xiangsheng Liu, Jinlei Wang, Kefeng Ren, Jian Ji. Zwitterionic polycarboxybetaine coating functionalized with REDV peptide to improve selectivity for endothelial cells. Journal of Biomedical Materials Research Part A, 6( 2012 ), 1387-1397