Research @ Faculty of Science 2023

DEPARTMENT OF FOOD SCIENCE AND NUTRITION 153 Email christina.poon@polyu.edu.hk Qualification BSc (The University of Leeds) MPhil (The Chinese University of Hong Kong) PhD (The Chinese University of Hong Kong) ORCID ID 0000-0002-4569-876X Representative Publications • Front. Endocrinol. 2022, 13:863448 • Journal of Bone and Mineral Research. 2022, 37(1):121-136 • Phytomedicine. 2021, 82:153413 • Handbook of Experimental Pharmacology. 2020, 262:499-518 • Journal of the Endocrine Society. 2019, 4(2):bvz025 • Frontiers in Pharmacology. 2018, 9:474 • European Journal of Pharmacology. 2015, 767:30-40 • British Journal of Pharmacology. 2010, 161:1086-1098 Patent • Inventor of a China Patent - 潘翠華, 黃文秀, 一種整合 素α5β1作為靶點在篩選用於預防和/或治療骨流失的 藥物中的應用, Application No. 2023103808692, filed on 13/04/2023 Awards and Achievements PI of one HMRF, one Start-up fund and one HK PolyU internal fund. Co-I of one GRF, one HMRF and three HK PolyU internal funds. • Council member, World Federation of Chinese Medicine Societies (Feb 2023-Present) • Study of kidney-tonifying Chinese herbal medicine Cistanches Herba (CH) and its bioactive compounds on myogenesis for the management of sarcopenia (Ref. P0045265); As PI: Funding for Research Centres (under PAIR): RCMI Tier 2 Seed Fund: Exploratory Research (HK$150,000), 2023-2024 • Study of the use of Chinese herbal medicine Er Zhi Wan for management of osteosarcopenia (Ref.: 19200411); As PI: Health and Medical Research Fund (HK$1,484,580), 20222025 • Mechanistic study of kidney-tonifying Chinese herbal medicine Fructus Ligustri Lucidi (FLL) and its bioactive compounds on skeletal muscle regeneration for the management of sarcopenia (Ref.: P0042442); As PI: HK PolyU Start-up Fund for RAPs (HK$250,000), 2022-2024 Dr POON Chui-wa Christina Research Assistant Professor Research Overview Dr Poon is a pharmacologist with extensive experience in studying bone metabolism and potential therapeutic approaches for musculoskeletal disorders, especially the natural compounds of herbal medicines. Her research interests include the study of the mechanism of actions of phytochemicals and traditional Chinese medicine for the management of osteoporosis and sarcopenia (osteosarcopenia). RNA sequencing analysis of the long-term icariin treatment of bone marrow stromal cells (BMSCs) isolated from OVX rats. Gene ontology (GO) functional analysis of differentially expressed genes (DEGs) in the comparison between OVX and icariin at 500 ppm. (Phytomedicine. 2021, 82:153413)

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