Research @ Faculty of Science 2023

DEPARTMENT OF FOOD SCIENCE AND NUTRITION 159 Email man-sau.wong@polyu.edu.hk Qualification BSc (University of Illinois at Urbana-Champaign) PhD (University of Chicago) ORCID ID 0000-0002-0729-8618 Representative Publications • Nutrients. 2022, 14(22):4718 • Nutrients. 2021, 13(9):2943 • Phytomedicine. 2021, 82:153413 • Phytotherapy Res. 2021, 35(3):1456-1467 • J. Nutr. 2018, 148:1895–1902 • Front. Pharmacol. 2018, 9:932 • Nutrients. 2018, 10(2). pii: E247 • Br. J. Pharmacol. 2010, 159(4):939-949 • J. Clin. Endo. Metab. 2004, 89(5):2351-2359 • J. Clin. Endo. Metab. 2002, 87(8):3691-3695 Patents • China Patent No. 201010103723.6 • China Patent No. ZL201610102211.5 • China Patent No. ZL 201711061004.0 • China Patent No: ZL 201920764988.1 Awards and Achievements • The World’s Top 2% most-cited scientists by Stanford University (Medicinal and Biomolecular Chemistry), 2022 • Registered Nutritionist, Association for Nutrition (UK), 20212024 • Certified Food Scientist, Institute of Food Technologist, 2013 to 2023 • Higher Education Outstanding Scientific Research Output Awards (Science and Technology) from the Ministry of Education 2013, Second Class Prize in Scientific and Technological Progress Award • Shenzhen Virtual University Park National Technology Project Pioneer Award, Shenzhen Technology and Innovation Committee, 2012 • Highest International Consultancy Award, Outstanding Professional Services Awards 2011, PolyU Technology and Consultancy Co. Ltd. Prof. WONG Man-sau Professor Director of Research Centre for Chinese Medicine Innovation Research Overview My research focuses on studying the health benefits and mechanisms of actions of nutrients, phytochemicals and Chinese herbal medicine, especially for the management of bone health. My research interests include the use of traditional Chinese medicine (TCM) for the prevention and treatment of postmenopausal osteoporosis; the study of the molecular actions of bone protective phytochemicals; the regulation of vitamin D and Ca metabolism by hormone and dietary factors; the mechanisms of actions of TCM-derived phytoestrogens in achieving tissue selectivity; drug-herbs interactions between the use of selective estrogen receptor modulators (SERMs) and Chinese medicine used for the management of menopausal syndromes as well as the role of gut microbiota in mediating the therapeutic actions of Chinese medicine. The goal of my research work is to support the development of scientific/ evidence-based functional food and TCM-derived product.

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