DEPARTMENT OF APPLIED BIOLOGY & CHEMICAL TECHNOLOGY 29 Email larry.chow@polyu.edu.hk Qualification BSc (University of London) ScD (Harvard University) ORCID ID 0000-0002-9222-8322 Prof. CHOW Ming-cheung Larry Professor Head of Department Research Overview We are interested in studying the molecular mechanisms underlying drug resistance in cancer; early phase drug discovery projects particularly in our patented technology of using flavonoid dimers and green tea polyphenols in reversing cancer drug resistance and in infectious diseases like leishmaniasis; mechanism of how PfCRT in mediating chloroquine resistance; mechanism of various oncogenes like ITGA2, SALL4 and SND1. Representative Publications • J Med Chem 2019, 62(18), 8578-8608 • Curr Med Chem 2019, 26(25), 4799-4831 • J Med Chem 2018, 61(22), 9931-9951 • Eur J Med Chem 2017, 125, 795-806 • J Med Chem 2015, 58(11), 4529-4549 • Mol Pharm 2015, 12(10), 3507-3517
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