Research @ Faculty of Science 2023

DEPARTMENT OF APPLIED BIOLOGY & CHEMICAL TECHNOLOGY 37 Email ga-lai.law@polyu.edu.hk Qualification MChem (The University of Manchester) PhD (The University of Hong Kong) ORCID ID 0000-0002-2192-6887 Prof. LAW Ga-lai Professor Research Areas Prof. Law’s research area focuses on frontier lanthanide chemistry for imaging, diagnostics and development of new materials. Representative Publications • ‘Helicate-to-tetrahedron transformation of chiral lanthanide supramolecular complexes induced by ionic radii effect and linker length’ King-Him Yim, Chi-Tung Yeung, Michael R. Probert, Wesley Ting Kwok Chan, Lewis E. Mackenzie, Robert Pal, Wing-Tak Wong,* Ga-Lai Law*, Communications Chemistry, 4(1), 116-125, 2021 • ‘Unusual Magnetic Field Responsive Circularly Polarized Luminescence Probes with Highly Emissive Chiral Eu(III) Complexes’, Junhui Zhang, Lixiong Dai, Alexandra M. Webster, Wesley Ting Kwok Chan, Steven L. Cobb, Ga-Lai Law* Angewandte Chemie International Edition 60(2), 1004-1010, 2021 • ‘Design of Functional Chiral Cyclen-Based Radiometal Chelators for Theranostics’ Lixiong Dai, Junhui Zhang, Carlos Tinlong Wong, Wesley Ting Kwok Chan Chan, Xiaoxi Ling, Carolyn J Anderson, Ga-Lai Law*, Inorganic Chemistry, 60(10), 7082-7088, 2021 • ‘Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(III) luminescence and unprecedented two-photon excitation properties’, Lixiong Dai, Wai-Sum Lo, Yanjuan Gu, Qingwu Xiong, Ka-Leung Wong, Wai-Ming Kwok, Wing-Tak Wong*, Ga-Lai Law*, Chemical Science, 10(17), 4550-4559, 2019 • ‘Chirality and chiroptics of lanthanide molecular and supramolecular assemblies’, Ho-Yin Wong, Wai-Sum Lo, King-Him Yim, Ga-Lai Law*, Chem, 5(12), 3058-3095, 2019 • ‘Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications’, Lixiong Dai, Chloe M Jones, Wesley Ting Kwok Chan, Tiffany A Pham, Xiaoxi Ling, Eric M Gale, Nicholas J Rotile, William Chi-Shing Tai, Carolyn J Anderson*, Peter Caravan*, Ga-Lai Law*, Nature Communications, 9(1), 857-867, 2018 • ‘Chiral Transcription in Self-Assembled Tetrahedral Eu4L6 Chiral Cages Displaying Sizable Circularly Polarized Luminescence’ Chi-Tung Yeung, King-Him Yim, Ho-Yin Wong, Robert Pal, Wai-Sum Lo, Siu-Cheong Yan, Melody Yee-Man Wong, Dmitry Yufit, Danil E. Smiles, Laura J. McCormick, Simon J. Teat, Laura J. McCormick, David K. Shuh, Wing-Tak Wong* & Ga-Lai Law*, Nature Communications, 8(1), 1128-1138, 2017 • ‘EBNA1-targeted probe for the imaging and growth inhibition of tumours associated with the Epstein–Barr virus’, Lijun Jiang, Rongfeng Lan, Tao Huang, Chi-Fai Chan, Hongguang Li, Sam Lear, Jingyi Zong, Wing-Yan Wong, Magnolia Muk-Lan Lee, Brandon Dow Chan, Wai-Lun Chan, Wai-Sum Lo, Nai-Ki Mak*, Maria Li Lung, Hong Lok Lung, Sai Wah Tsao, Graham S Taylor, Zhao-Xiang Bian, William CS Tai, Ga-Lai Law*, Wing-Tak Wong*, Steven L Cobb, * Ka-Leung Wong*, Nature Biomedical Engineering, 1(4), 0042, 2017 • ‘Lanthanide supramolecular helical diastereoselective breaking induced by point chirality: mixture or P-helix, M-helix’, ChiTung Yeung, Wesley Ting Kwok Chan, Siu-Cheong Yan, KwanLeung Yu, King-Him Yim, Wing-Tak Wong*, Ga-Lai Law*, Chemical Communications, 51(3), 592-595, 2015 • ‘In vivo selective cancer-​tracking gadolinium eradicator as new-​generation photodynamic therapy agent’, Tao Zhang; Rongfeng Lan; Chi-Fai Chan; Ga-Lai Law*; Wai-Kwok Wong; Ka-Leung Wong, Proceedings of the National Academy of Sciences of the United States of America 111(51), E5492-E5497, 2014

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