DEPARTMENT OF APPLIED BIOLOGY & CHEMICAL TECHNOLOGY 59 Email zhongping.yao@polyu.edu.hk Qualification BSc, MSc (Fudan University) PhD (The Hong Kong University of Science and Technology) Postdoc (University of Maryland, College Park) Postdoc (University of Cambridge) ORCID ID 0000-0003-3555-9632 Prof. YAO Zhongping Professor Research Overview Prof. Yao conducts interdisciplinary research in mass spectrometry, analytical chemistry, chemical biology and multi-omics. He develops and applies mass spectrometry-based approaches to address fundamental and applied problems in chemistry, biology, medicine, information science, food safety, etc. His current research interests include: Molecular data storage; protein structures, dynamics and interactions; molecular assembly and recognition; authentication of edible oils; mechanistic study and biomarker discovery of diseases and biological processes. Representative Publications • Trends Anal. Chem. 2022, 157, 116759 • Nat. Plants 2021, 7, 1335-1346 • Proc. Natl. Acad. Sci. USA 2021, 118, e2101287118 • J. Biol. Chem. 2021, 297, 100980 • Nat. Commun. 2021, 12, 4242 • Food Chem. 2021, 334, 127601 • J. Am. Chem. Soc. 2020, 124, 13756-13767 • Anal. Chem. 2020, 92, 8201-8208 • Trends Anal. Chem. 2020, 124, 115801 • Neuron 2020, 105, 276-292 Patents • US Patents: No. 11315023; No. 11302421B2; No. 10859552B2 • Taiwan Patent: No. I714784B • China Patents: No. 201710588321.1; No. 201410538320.2; No. 201320743737.3; No. 201310291014.9 Awards and Achievements • Associate Editor, Frontiers in Chemistry, 2022-present • Principal Coordinator for RGC RIF project “Data Storage and Retrieval using Peptides and Tandem Mass Spectrometry”, 2020-2025 • Panel Member for the RGC Physical Sciences Subject (Joint Research Schemes), 2019-present • Assessment Panel Member for RGC the Biology and Medicine Subject (Competitive Research Funding Schemes for the Local Self-financing Degree Sector), 2019-present • Most Valued Project Award (Merit), The Hong Kong Polytechnic University, 2019 • President, The Hong Kong Society of Mass Spectrometry, 2018-2022 • Series Editor for the book series on New Developments in Mass Spectrometry, The Royal Society of Chemistry, 2018-present • Member of Organic Analysis Committee, The Chinese Chemical Society, 2016-present • “Changbaishan Scholar” Chair Professor, Jilin Province, China, 2015-2018 • Editorial Board Member for Analytica Chimica Acta, Chemical Biology Letters, Mass Spectrometry, Natural Products Chemistry & Research, Rapid Communications in Mass Spectrometry The process of storing and retrieving data into and from peptides A volcano plot for the quantitative proteomics analysis of transport vesicles Binding with β-lactamase inhibitory protein (BLIP) caused significant hydrogen/deuterium exchange difference of TEM1 β-lactamase
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