Research @ Faculty of Science 2023

DEPARTMENT OF APPLIED BIOLOGY & CHEMICAL TECHNOLOGY 64 Email q.zhao@polyu.edu.hk Qualification BEng (Xi'an Jiaotong University) PhD (The University of Hong Kong) Postdoc (University of California, San Francisco) ORCID ID 0000-0003-2244-6516 Dr ZHAO Qian Associate Professor Research Overview Our research lies in the interface of chemical biology and proteomics. We focus on two topics and use interdisciplinary approaches in biology, chemistry and mass spectrometry. The first topic is to reveal and investigate novel functional peptides, including cytosolic peptides and immunopeptides, particularly those encoded by small open reading frames. The second topic is to develop novel chemical proteomic approaches that facilitate the discovery of innovative anticancer therapies. Representative Publications • Molecular & Cellular Proteomics. 2023; 22(1), 100480 • Cell. 2023; 186(1), 98-111.e21 • ACS Chemical Biology. 2022; 17(8): 2003-9 • Nucleic Acids Research. 2022; 50(12): 6601-17 • Biological Chemistry. 2022; 403(4): 445-51 • ChemBioChem 2022; 23(8), e202100534 • Journal of the American Society for Mass Spectrometry. 2021; 32(9): 2346-57 • Nucleic Acids Research. 2021; 49(11): 6165-80 • Cancer Research. 2021; 81(12): 3229-40 • Analytical Chemistry. 2018; 90(18): 11092-8 • Science. 2018; 359(6382): 1416-21 • Proceedings of the National Academy of Sciences USA. 2017; 115(10): 2353-8 • Journal of the American Chemical Society. 2017; 139(2): 680-5 • Analytical Chemistry. 2017; 89(19): 10368-75 • Chemical Science. 2015; 6(7): 4124-30 • Angewandte Chemie-International Edition. 2013; 52(18) 4883-6 Awards and Achievements • Emerging Investigators in Mass Spectrometry, Journal of the American Society for Mass Spectrometry, 2021 • Gordon Conference Travel Award, 2015 • Utrecht University short-stay Fellowship, 2011 Professional Service • Editorial board member of Molecular & Cellular Proteomics and Chinese Chemical Letters • Council member of the Human Proteome Organization (HUPO)

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