Promethion Metabolic Cage System

Major Functions / Key Features

The Promethion metabolic Cage Systems are designed for metabolic and behavioral phenotyping of mice by measuring and recording numerous parameters in a user-adjustable environmental control cabinet. O2 consumption and CO2 production by mice are measured to devise the respiratory quotient that reflects energy expenditure. The horizontal and vertical movement (i.e., XYZ-axis) of the mice in the metabolic cage and their movement on the running wheels are monitored for a quantitative measurement of physical activity. The food (with access control device) and water consumption, as well as the body masses of mice are also recorded by the system. These metabolic and behavioral data are recorded real-time and can later be comprehensively analyzed with the supplied software.

Specifications:

Two sets of 8-cage systems:

• Food intake monitoring unit with access control module
• Water intake monitoring unit
• Body mass and cage enrichment device
• Wheel monitoring system
• 3D infrared beam break array (position resolution: physical beam spacing 1 cm; effective resolution: 0.25 cm)

Promethion flow generators:

• Flow rate: 2000 mL/minute for mice
• Flow resolution: 0.001 mL/min

Promethion GA-3 Gas Analyzers

• Gas resolution: 0.0001% (O₂, CO₂)

Environmental control cabinet:

• Range: 3 to 40 °C
• Interior light: manual or programmable timer control

Applications:

• Metabolic/behavioral phenotyping of mice