PolyU Scholars Hub
Dr HSU Chun Liang
Kuok Group Young Scholar in Aging and Neuroimaging, Assistant Professor, Presidential Young Scholar
PhD (UBC), MSc (UBC), BSc (UBC)
- +852 2766 6755
- chun-liang.hsu@polyu.edu.hk
ORCID ID
SCOPUS IDBiography
Dr Hsu graduated with a PhD in Rehabilitation Sciences from the University of British Columbia. After obtaining his PhD, Dr Hsu was awarded the competitive Canadian Institutes of Health Research (CIHR) Fellowship to pursue postdoctoral training at the prestigious Hinda and Arthur Marcus Institute for Aging Research, Harvard Medical School.
Dr Hsu primarily utilises magnetic resonance imaging to conduct his work. His research interests include: 1) understanding the underlying neural basis of functional impairments and its relationship with cognition and mobility among aging clinical populations; and 2) identifying and evaluating CNS-related interventions to promote cognitive and mobility outcomes in clinical populations. Specifically, Dr Hsu uses a combination of advanced neuroimaging techniques to examine the neural signatures of impaired cognitive function and mobility as well as to investigate how they may be modulated by specific interventions. Dr Hsu has experience working with a variety of clinical populations, including older individuals with stroke, mild cognitive impairment, and impaired mobility.
Education and Academic Qualifications
Doctor of Philosophy in Rehabilitation Sciences, University of British Columbia
Master of Science in Rehabilitation Sciences, University of British Columbia
Bachelor of Science, University of British Columbia
Master of Science in Rehabilitation Sciences, University of British Columbia
Bachelor of Science, University of British Columbia
Research Interests
Research Output
Hsu CL, Best JR, Voss MW, Handy TC, Beauchet O, Lim C, Liu-Ambrose T. Functional neural correlates of slower gait among older adults with mild cognitive impairment. J Gerontol A Biol Sci Med Sci. 2018 Feb 17. doi: 10.1093/gerona.gly027
Hsu CL, Best JR, Davis JC, Nagamatsu LS, Wang S, Boyd LA, Hsiung RGY, Voss MW, Eng JJ, Liu-Ambrose T. Aerobic exercise promotes executive functions and impacts functional neural activity among older adults with vascular cognitive impairment. BJSM. 2017 Apr 21. pii: bjsports-2016-096846. doi: 10.1136/bjsports-2016-096846
Hsu CL, Best JR, Chui BK, Voss MW, Handy TC, Bolandzadeh N, Liu-Ambrose T. Structural neural correlates of falls status and subsequent decline in executive functions: A 12-month prospective study. Exp Geronto. 2016 Apr 11;80:27-35. doi: 10.1016/j.exger.2016.04.001
Falck RS, Hsu CL, Silva NCBS, Li LC, Best JR, Liu-Ambrose T. The independent associations of physical activity and sleep with neural activity during an inhibitory task: Cross-sectional results from the MONITOR-OA study. J Sleep Res. 2022 Jul 12:e13692. doi: 10.1111/jsr.13692
Boa Sorte Silva NC, Dao E, Hsu CL, Tam RC, Stein R, Alkeridy W, Laule C, Vavasour IM, Liu-Ambrose T. Myelin content and gait impairment in older adults with cerebral small vessel disease and mild cognitive impairment. Neurobiol Aging. 2022 Jul 20;119:56-66. doi: 10.1016/j.neurobiolaging.2022.03.020
Crockett RA, Falck RS, Dao E, Hsu CL, Tam R, Alkeridy W, Liu-Ambrose T. Sweat the fall stuff: Physical activity moderates the association of white matter hyperintensities with falls risk in older adults. Front Hum Neurosci. 2021 May 21;15:671464. doi: 10.3389/fnhum.2021.671464. PMID: 34093153; PMCID: PMC8175638.
Crockett RA, Hsu CL, Dao E, Tam R, Eng JJ, Handy TC, Liu-Ambrose T. Painting by lesions: White matter hyperintensities disrupt functional networks and global cognition. Neuroimage. 2021 Apr 18:118089. doi: 10.1016/j.neuroimage.2021.118089. Epub ahead of print. PMID: 33882347.
Ten Brinke LF, Hsu CL, Erickson KI, Handy TC, Liu-Ambrose T. Functional connectivity and response inhibition: Effects of an 8-week randomized controlled trial of computerized cognitive training. J Alzheimers Dis. 2021;80(4):1525-1537. doi: 10.3233/JAD-200844. PMID: 33720882.
Liu-Ambrose T, Davis JC, Best JR, Dian L, Madden K, Cook W, Hsu CL, Khan KM. Effect of a home-based exercise program on subsequent falls among community-dwelling high-risk older adults after a fall: A randomized clinical trial. JAMA. 2019 Jun 4;321(21):2092-2100. doi: 10.1001/jama.2019.5795
Hsu CL, Best JR, Davis JC, Nagamatsu LS, Wang S, Boyd LA, Hsiung RGY, Voss MW, Eng JJ, Liu-Ambrose T. Aerobic exercise promotes executive functions and impacts functional neural activity among older adults with vascular cognitive impairment. BJSM. 2017 Apr 21. pii: bjsports-2016-096846. doi: 10.1136/bjsports-2016-096846
Hsu CL, Best JR, Chui BK, Voss MW, Handy TC, Bolandzadeh N, Liu-Ambrose T. Structural neural correlates of falls status and subsequent decline in executive functions: A 12-month prospective study. Exp Geronto. 2016 Apr 11;80:27-35. doi: 10.1016/j.exger.2016.04.001
Falck RS, Hsu CL, Silva NCBS, Li LC, Best JR, Liu-Ambrose T. The independent associations of physical activity and sleep with neural activity during an inhibitory task: Cross-sectional results from the MONITOR-OA study. J Sleep Res. 2022 Jul 12:e13692. doi: 10.1111/jsr.13692
Boa Sorte Silva NC, Dao E, Hsu CL, Tam RC, Stein R, Alkeridy W, Laule C, Vavasour IM, Liu-Ambrose T. Myelin content and gait impairment in older adults with cerebral small vessel disease and mild cognitive impairment. Neurobiol Aging. 2022 Jul 20;119:56-66. doi: 10.1016/j.neurobiolaging.2022.03.020
Crockett RA, Falck RS, Dao E, Hsu CL, Tam R, Alkeridy W, Liu-Ambrose T. Sweat the fall stuff: Physical activity moderates the association of white matter hyperintensities with falls risk in older adults. Front Hum Neurosci. 2021 May 21;15:671464. doi: 10.3389/fnhum.2021.671464. PMID: 34093153; PMCID: PMC8175638.
Crockett RA, Hsu CL, Dao E, Tam R, Eng JJ, Handy TC, Liu-Ambrose T. Painting by lesions: White matter hyperintensities disrupt functional networks and global cognition. Neuroimage. 2021 Apr 18:118089. doi: 10.1016/j.neuroimage.2021.118089. Epub ahead of print. PMID: 33882347.
Ten Brinke LF, Hsu CL, Erickson KI, Handy TC, Liu-Ambrose T. Functional connectivity and response inhibition: Effects of an 8-week randomized controlled trial of computerized cognitive training. J Alzheimers Dis. 2021;80(4):1525-1537. doi: 10.3233/JAD-200844. PMID: 33720882.
Liu-Ambrose T, Davis JC, Best JR, Dian L, Madden K, Cook W, Hsu CL, Khan KM. Effect of a home-based exercise program on subsequent falls among community-dwelling high-risk older adults after a fall: A randomized clinical trial. JAMA. 2019 Jun 4;321(21):2092-2100. doi: 10.1001/jama.2019.5795
