教学人员
- QT504
- +852 2766 4890
- Sonata.Yau@polyu.edu.hk
- ResearchGate
ORCID ID
SCOPUS ID简历
邱博士于2005年取得香港科技大学生物化学系的学士学位，其后于2009年在香港大学解剖学系取得神经科学博士学位。在加入香港理工大学之前，她在2009年至2012年间获得香港大学博士后研究基金, 及在2012年至2015年获得加拿大维多利亚大学（不列颠哥伦比亚省）的博士后研究基金。她对使用不同的疾病动物模型去探讨如何促进大脑可塑性的非药物和药物治疗特别感兴趣。她目前的研究领域集中在对学习和记忆非常重要的大脑区域:海马体。她主力使用疾病动物模, 例如抑郁症和精神发育迟滞,去研究体育锻炼引起的海马体可塑性的基本机制, 并确定其相关的生物标志物, 从而研究体育锻炼对人类大脑健康状况的影响。此外, 她还研究海马可塑性潜在的认知功能障碍和低智力的治疗护理。她的研究工作使用大量的科研技术来评估海马的结构和功能，例如动物行为分析，电生理，免疫组织染色法和蛋白质印迹法等。
学历
- Bachelor of Science in Biochemistry, The Hong Kong University of Science and Technology
- Doctor of Philosophy, The University of Hong Kong
研究兴趣
研究成果
- Formolo AD, THY Lee, Yau SY. (2019). Increasing adiponergic system activity as a potential treatment for depressive disorder. Molecular Neurobiology https://doi.org/10.1007/s12035-019-01644-3
- Yau SY, Lee THY, Lee WL, Li LCK, Siu PM, Chan CCH. (2019) Effects of maternal exercise on adult hippocampal neurogenesis, temporal order memory and depression-like behaviour in adult female and male offspring. Front. Neurosci. https://doi.org/10.3389/fnins.2019.00470
- Yau SY, Bettio L, Vetrici M, Truesdell A, Chiu C, Chiu J, Truesdell E, Christie BR. (2018) Chronic minocycline treatment improves hippocampal neuronal structure, NMDA receptor function, and memory processing in Fmr1 knockout mice. Neurobiology of Disease. 2018 Jan 29;113:11-22
- Wang BL , Li A, Li XM, Ho WLP , Wu DH, Wang XQ, Liu ZH, Wu KKL, Yau SY, Xu AM, Cheng KK. (2018) Activation of hypothalamic RIP-Cre neurons promotes beiging of WAT via sympathetic nervous system. EMBO Report. 2018 Feb 21. pii: e44977
- Supriya R, Yu AP, Lee PH, Lai CW, Cheng KK, Yau SY, Chan LW, Yung BY, Siu PM. (2018) Yoga training modulates adipokines in adults with high-normal blood pressure and metabolic syndrome. Scand J Med Sci Sports. Mar;28(3):1130-1138
- Yau SY, Bostrom C, Chiu J, Ghilan M, Chiu CY, Hryciw BN, Eadie BD, Christie BR. (2016) Impaired bidirectional NMDA receptor dependent synaptic plasticity in the dentate gyrus of adult female Fmr1 heterozygous knockout mice. Neurobiology of Disease 19 (96):261-270
- Bostrom C, Yau SY, Majaess N, Vetrici M, Gil-Mohapel J, Christie BR. (2016) Hippocampal deficits are associated with learning and memory impairment in Fragile X Syndrome. Neuroscience and Biobehavioral Reviews 68:563-574
- Yau SY, Li A, Loo R, Ching YP, Christie BR, Lee TMC, Xu AM, So KF. (2014) Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin. PNAS. 111 (44): 15810-15815
- Lee TMC, Wong ML, Lau BMW, Lee JCD, Yau SY, So KF. (2014) Aerobic exercise interacts with neurotrophic factors to predict cognitive functioning in adolescents. Psychoneuroendocrinology 39: 214—224
- Yau SY, Lau BWM, Tong JB, Wong R, Ching YP, Qiu G, Tang SW, Lee TMC, So KF. (2011) Hippocampal neurogenesis and dendritic plasticity support running-enhanced memory and depression-like behavior in stressed rats. PLosOne 6(9):e24263.
