- Y857
- +852 3400 8867
- yangxian.yang@polyu.edu.hk
ORCID ID
SCOPUS IDResearch Overview
My research focuses on biochemical and structural studies of telomeric proteins to investigate the molecular mechanism of how telomere proteins regulate Variable Surface Glycoprotein (VSG) switching and maintain the telomere integrity and stability in Trypanosoma brucei.
Research Interests
Achievements
- Doctor of Philosophy, The Hong Kong Polytechnic University
- Master of Science, Jinan University (mainland of China)
- Bachelor of Science, Hunan traditional Chinese medicine University (mainland of China)
1. Amit Kumar Gaurav*; Marjia Afrin*; Xian Yang*; Arpita Saha; Xuehua Pan; Zeyang Ji; Mingjie Zhang; Yanxiang Zhao; Bibo Li. The RRM-mediated RNA binding activity in T. brucei RAP1 is essential for VSG monoallelic expression. [J]. Nature Communications, 2023, 14(1): 1576.
2. Afrin, M.*, Gaurav, A. K.*, Yang X., Pan, X., Zhao, Y., & Li, B. (2020). TbRAP1 has an unusual duplex DNA binding activity required for its telomere localization and VSG silencing. Science advances, 6(38), eabc4065.
