Research Assistant Professor

PolyU Scholars Hub

Dr Julie LI

BVetMed (ZJU), MPhil (UCAS), PhD (CUHK)

ST524
+852 2766 4842
ye-julie.li@polyu.edu.hk
Sports Science and Musculoskeletal Health

PolyU Scholars Hub

ORCID ID

SCOPUS ID

Biography

Dr Ye Li (Julie) received her bachelor’s degree in veterinary medicine at Zhejiang University, her MPhil in Biomedical Engineering at the University of Chinese Academy of Sciences, and her PhD in Orthopaedics and Traumatology at The Chinese University of Hong Kong. Prior to joining The Hong Kong Polytechnic University, she worked as a postdoctoral fellow at The Chinese University of Hong Kong and the Hong Kong Institute of Science & Innovation of Chinese Academy of Sciences respectively.

Dr Li has research experience in magnesium-based products for bone defect healing, distraction osteogenesis for bone defect healing, the delivery of CGRP for tissue healing, anterior cruciate ligament (ACL) reconstruction, and pulsed electromagnetic field (PEMF) for cartilage repair. Currently, Dr Li is interested in wearable devices for osteoarthritis rehabilitation, traditional Chinese medicine (TCM) for tissue regeneration, and musculoskeletal disease healing.

Education and Academic Qualifications

• Bachelor of Veterinary Medicine, Zhejiang University
• Master of Philosophy in Biomedical Engineering, University of Chinese Academy of Sciences
• Doctor of Philosophy in Orthopaedics and Traumatology, The Chinese University of Hong Kong

Professional Qualifications

Practising Veterinary Surgeon

Research Interests

Research Output

Li Y, Xu J, Mi J, He X, Pan Q, Zheng L, Zu H, Chen Z, Dai B, Li X, Pang Q, Zou L, Zhou L, Huang L, Tong W, Li G, Qin L. Biodegradable magnesium combined with distraction osteogenesis synergistically stimulates bone tissue regeneration via CGRP-FAK-VEGF signaling axis. Biomaterials, 2021, 275: 120984.
Lai Y, Li Y (equal first author), Cao H, Long J, Wang X, Li L, Li C, Jia Q, Teng B, Tang T, Peng J, Eglin D, Alini M, Grijpma D, Richards G, Qin L. Osteogenic magnesium incorporated into PLGA/TCP porous scaffold by 3D printing for repairing challenging bone defect. Biomaterials, 2019, 197: 207-219.
Li Y, Pan Q, Xu J, Li G, Qin L. Overview of methods for enhancing bone regeneration in distraction osteogenesis: Potential roles of biometals. Journal of Orthopaedic Translation, 2021, 27: 110-118.
Pan Q, Li Y (equal first author), Li Y, Lin S, Li G. Local administration of allogeneic or autologous bone marrow-derived mesenchymal stromal cells enhances bone formation similarly in distraction osteogenesis. Cytotherapy, 2021, 23(7): 590-598.
Li Y, Chen SK, Li L, Qin L, Wang X, Lai Y. Bone defect animal models for testing efficacy of bone substitute biomaterials. Journal of Orthopaedic Translation, 2015, 3(3): 95-104.
Li Y, Li L, Li Y (equal first author), Feng L, Wang B, Wang M, Wang H, Zhu M, Yang Y, Waldorff E, Zhang N, Viohl I, Lin S, Bian L, Lee W, Li G. Enhancing cartilage repair with optimized hydrogel-based scaffold with pulsed electromagnetic field. Bioactive Materials, 2023, 22: 312-324.
He X, Li Y (equal first author), Miao H, Sun J, Ong M, Zu H, Li W. The bioactive Mg-Zn-Gd wire enhances musculoskeletal regeneration: An in vitro study. Crystals, 2022, 12(9): 1287.
Li X, Dai B, Guo J, Zhu Y, Xu J, Xu S, Yao Z, Chang L, Li Y, He X, Chow D, Zhang S, Yao H, Tong W, Ngai T, Qin L. Biosynthesized bandages carrying magnesium oxide nanoparticles induce cortical bone formation by modulating endogenous periosteal cells. ACS Nano, 2022.
Yao Z, Yuan W, Xu J, Tong W, Mi J, Chow H, Ho P, Li Y, Yao H, Li X, Xu S, Guo J, Zhu Q, Bian L, Qin L. Magnesium‐encapsulated injectable hydrogel and 3D‐engineered polycaprolactone conduit facilitate peripheral nerve regeneration. Advanced Science, 2022: 2202102.
Pang Q, Xu Y, Huang L, Li Y, Lin Y, Hou Y, Hung V, Qi X, Ni X, Li M, Jiang Y, Wang O, Xing X, Qin L, Xia W. Bone geometry, density, microstructure and biomechanical properties in the distal tibia in patients with primary hypertrophic osteoarthropathy assessed by second-generation HR-pQCT. Journal of Bone and Mineral Research, 2022, 37(3): 484-493.
Dai B, Xu J, Li X, Huang L, Hopkins C, Wang H, Yao H, Mi J, Zheng L, Wang J, Tong W, Chow H, He X, Li Y, He X, Hu P, Chen Z, Zu H, Li Y, Yao Y, Jiang Q, Qin L. Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis. Nature Communication, 2022, 13(1): 1-17.
Mi J, Xu J, Yao Z, Yao H, Li Y, He X, Dai B, Zou L, Tong W, Zhang X, Hu P, Ruan Y, Tang N, Guo X, Zhao J, He J, Qin L. Implantable electrical stimulation at dorsal root ganglions accelerates osteoporotic fracture healing via calcitonin gene-related peptide. Advance Science, 2022, 9(1): 2103005.
Mi J, Xu J, Yao H, Li X, Tong W, Li Y, Dai B, He X, Chow D, Li G, Lui K, Zhao J, Qin L. Calcitonin gene-related peptide enhances distraction osteogenesis by increasing angiogenesis. Tissue Engineering Part A, 2021, 27(1-2): 87-102.
He X, Li Y, Guo J, Xu J, Zu H, Huang L, Ong M, Yung S, Qin L. Biomaterials developed for facilitating healing outcome after anterior cruciate ligament reconstruction: Efficacy, surgical protocols, and assessments using preclinical animal models. Biomaterials, 2020: 120625.
Zu H, Chau K, Pan L, Dreyer C, Chow D, Huang L, Zheng L, Tong W, Li X, Chen Z, He X, Zhang R, Mi J, Li Y, Dai B, Wang J, Xu J, Liu K, Lu J, Qin L. Comparison of modified injection molding and conventional machining in biodegradable behavior of perforated cannulated magnesium hip stent. Journal of Materials Science & Technology, 2021. 021, 63: 145-160.
Xu J, Wang J, Chen X, Li Y, Mi J, Qin L. The effects of calcitonin gene-related peptide on bone homeostasis and regeneration. Current Osteoporosis Reports, 2020, 18(6): 621-632.
Pan Q, Li Y, Xu J, Kang Y, Li Y, Wang B, Yang P, Lin S, Li G. The effects of tubular structure on biomaterial aided bone regeneration in distraction osteogenesis. Journal of Orthopaedic Translation,2020, 25: 80-86.
Li L, Zhang M, Li Y, Zhao J, Qin L, Lai Y. Corrosion and biocompatibility improvement of magnesium-based alloys as bone implant materials: A review. Regenerative Biomaterials, 2017, 4(2): 129-137.
Ma R, Lai Y, Li L, Tan H, Wang J, Li Y, Tang T, Qin L. Bacterial inhibition potential of 3D rapid-prototyped magnesium-based porous composite scaffolds – An in vitro efficacy study. Scientific Reports, 2015, 5: 13775.
Cao HJ, Zheng LZ, Wang N, Wang L, Li Y, Li D, Lai Y, Wang X, Qin L. Src blockage by siRNA inhibits VEGF-induced vascular hyperpermeability and osteoclast activity – An in vitro mechanism study for preventing destructive repair of osteonecrosis. Bone, 2015, 74: 58-68.