PolyU scientists develop biomimetic nanosheet for cancer therapy and imaging
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The biology and chemical experts of PolyU have been dedicated to new drug development over the years, and have achieved some significant breakthroughs especially in cancer treatment. A research team from PolyU recently developed biomimetic nanomaterials as part of the University’s endeavours in fighting against cancer.
Led by Professor Wing-tak Wong, Chair Professor of Chemical Technology of the Department of Applied Biology and Chemical Technology (also the Deputy President and Provost of PolyU), the research team used two-dimensional nanosheets (FePSe3) to develop a novel type of biomimetic nanosheet with a multi-modal imaging function, which can track tumour development and treatment processes in real time. By harnessing two emerging cancer therapies, namely immunotherapy and photothermal therapy, the biomimetic nanosheet enables effective and precise treatment of tumours, which will significantly improve the therapeutic outcome of tumours, reduce side effects and increase patients’ survival rates.
Prof Wong said, “The novel biomimetic nanomaterials developed by PolyU provide a practical design blueprint for the development of a new generation of cancer theranostics agents which have high targeting ability, efficacy and safety.”
With positive results from mice, the team hopes to further test it on larger animals, then move on to clinical studies. The research findings have been published in the prestigious international journal Advanced Science.
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