Academic Staff
Dr Bingyang DAI
Research Assistant Professor
- GH139
- +852 2766 7628
- bingyang.dai@polyu.edu.hk
ORCID ID
SCOPUS ID
Google ScholarBiography
Dr. DAI, a Research Assistant Professor in the Department of Biomedical Engineering of The Hong Kong Polytechnic University, received his Ph.D. degree from Medical School of The Chinese University of Hong Kong in 2020. With clinical training background in Orthopaedics and in-depth understanding on musculoskeletal disorders, Dr. DAI has devoted himself as a clinician-scientist, excelling in exploring the pathophysiology and regeneration of musculoskeletal diseases.
Dr. DAI and his teammates contributed to the discovery of osteopontin as a key regulator from macrophages in visceral adipose tissue involved in bone loss (Nature Communications, 2022). Continuity of function was found in osteopontin linking infrapatellar fat pad with osteoarthritis progress (Advanced Science, 2023). Dr. DAI and his collaborators designed and synthesized various tissue mimetic membranes that are imparted the potential for translation. Several findings of magnesium-membrane accelerating bone defect or bone-to-tendon regeneration published in prestigious journals, including Advanced Materials (2025), ACS Nano (2022), ACS Appl. Mater. Interfaces (2022), Advanced Healthcare Materials (2022), etc. Combination of magnesium chloride and simvastatin attenuated the obesity-induced bone loss (Bioactive Materials, 2021). Inorganic magnesium silicate promptly potentiated burn skin wound repair (Advanced Functional Materials, 2023).
Professional Qualifications
- Certificate of practicing physician of National Health Commission of the People's Republic of China
- Guest Associate Editor in Bone Research, Frontiers in Endocrinology
- Guest Editor in Bioengineering
- Youth Editorial Bord Member of Extracellular Vesicles and Circulating Nucleic Acids
Academic and Professional Experience
- Postdoc Research Fellow, School of Medicine, the Chinese University of Hong Kong, 2020. 09 - 2024. 04
Research Interests
Research Output
- Yuwei Zhu, Bingyang Dai (equal-first), Shian Zhang, Jun Liu, Shunxiang Xu, Weiyang Liu, Xin Chen, Haozhi Zhang, Quan Li, Florence Ou-Suet Pang, Weiguo Li, Chunyi Wen, Ling Qin,* Jiankun Xu* and To Ngai*. Tissue Mimetic Membranes for Healing Augmentation of Tendon–Bone Interface in Rotator Cuff Repair. Advanced Materials. 31 January. 2025. (IF=27.4, at the year of accepted).
- Shunxiang Xu, Yuantao Zhang, Bingyang Dai (equal-first), Jiancun Rao, Fanyan Deng, Shi’an Zhang, Hongwei Shao, Xu Li, Zheyu Jin, Tongzhou Liang, Yongkang Yang, Yucong Li, Ziyi Chen, Wenxue Tong, Jiankun Xu *, Congqin Ning *, Ling Qin*. Green-prepared magnesium silicate sprays enhance the repair of burn-skin wound and appendages regeneration in rats and minipigs. Advanced Functional materials. 2023 November 26. (IF=19.924, at the year of accepted).
- Bingyang Dai, Yuwei Zhu, Xu Li, Zuru Liang, Shunxiang Xu, Shian Zhang, Zhe Zhang, Shanshan Bai, Wenxue Tong, Mingde Cao, Ye Li, Xiaobo Zhu, Wei Liu, Yuantao Zhang, Liang Chang, Patrick Shu-hang Yung, Kevin Ki-wai Ho, Jiankun Xu, To Ngai, and Ling Qin. Blockage of osteopontin-integrin 𝜷3 signaling in infrapatellar fat pad attenuates osteoarthritis in mice. Advanced Science. 2023 May. (IF=17.521, at the year of accepted).
- Xu Li, Bingyang Dai (equal-first), Jiaxin Guo, Yuwei Zhu, Jiankun Xu, Shunxiang Xu, Zhi Yao, Liang Chang, Ye Li, Xuan He, Dick Ho Kiu Chow, Shian Zhang, Hao Yao, Wenxue Tong, To Ngai*, and Ling Qin*. Biosynthesized bandages carrying magnesium oxide nanoparticles induce cortical bone formation by modulating endogenous periosteal cells. 2022 September 15. ACS Nano. (IF=18.027, at the year of accepted).
- Yuwei Zhu, Bingyang Dai (equal-first), Xu Li, Wei Liu, Jiangpeng Wang, Jiankun Xu,* Shunxiang Xu, Xuan He, Shian Zhang, Quan Li, Ling Qin,* and To Ngai*. Periosteum-Inspired Membranes Integrated with Bioactive Magnesium Oxychloride Ceramic Nanoneedles for Guided Bone Regeneration. 2022 Aug 26. ACS Appl Mater Interfaces. (IF=10.383, at the year of accepted).
- Bingyang Dai, Jiankun Xu, Xu Li, Le Huang, Chelsea Hopkins, Honglian Wang, Hao Yao, Jie Mi, Lizhen Zheng, Jiali Wang, Wenxue Tong, Dick Ho-kiu Chow, Ye Li, Xuan He, Peijie Hu, Ziyi Chen, Haiyue Zu, Yixuan Li, Yao Yao, Qing Jiang, and Ling Qin*. Macrophages in Epididymal Adipose Tissue Secrete Osteopontin to Regulate Bone Homeostasis. 2022 Jan; Nature Communications. (IF=17.694, at the year of accepted).
- Bingyang Dai, Xu Li, Jiankun Xu*, Yuwei Zhu, Le Huang, Wenxue Tong, Hao Yao, Dick Ho-kiu Chow, and Ling Qin**. Synergistic Effects of Magnesium Ions and Simvastatin on Attenuation of High-fat Diet-induced Bone Loss. Bioactive Materials. 2021 Feb. (IF=14.593, at the year of accepted).
- Xu Li, Jiankun Xu, Bingyang Dai (equal-first), Xinluan Wang, Quanyi Guo, Ling Qin*. Targeting Autophagy in Osteoporosis: from Pathophysiology to Potential Therapy. Review. Aging Res Rev. 2020 Sep. (IF=10.616, at the year of accepted).
- Xu Li, Tongzhou Liang, Bingyang Dai, Liang Chang, Yuan Zhang, Shiwen Hu, Jiaxin Guo, Shunxiang Xu, Lizhen Zheng, Hao Yao, Hong Lian, Yu Nie, Ye Li, Xuan He, Zhi Yao, Wenxue Tong, Xinluan Wang, Dick Ho Kiu Chow, Jiankun Xu*, and Ling Qin*. Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment. March 21, 2024. J Clin Invest. 2024. (IF=13.3, at the year of accepted).
- Xu Li, Bingyang Dai, Lizhen Zheng, Quanyi Guo, Jiang Peng, Jiankun Xu, Ling Qin. Nanoparticle–cartilage interaction: pathology-based intra-articular drug delivery for osteoarthritis therapy. Nano-Micro Letters. 2021 Jun. (IF=16.419, at the year of accepted).
- Bingyang Dai#, Lizhen Zheng, and Ling Qin* Section: Targeting Adipose Tissue: Therapeutic Strategies and Future Directions. Book: Adipose Tissue: Endocrine Functions, Health Implications, and Future Perspectives. eBook ISBN, 978-3-031-72570-8. Print ISBN, 978-3-031-72569-2. 17 December 2024.
