Academic Staff
Dr Quanxiang XIAN
Research Assistant Professor
Explores non-invasive ultrasound neuromodulation techniques for the treatment of brain disorders
- MN116
- salvia.xian@polyu.edu.hk
Biography
Dr Quanxiang Xian is currently a Research Assistant Professor in the Department of Biomedical Engineering (BME) at The Hong Kong Polytechnic University. She received her Ph.D. degree from the Department of Biomedical Engineering (BME) at The Hong Kong Polytechnic University in 2021. From 2021 to 2024, she served as a postdoctoral fellow at The Hong Kong Polytechnic University. Dr Xian is dedicated to conducting a comprehensive study of ultrasound neuromodulation mechanisms and advancing the possibilities for clinical applications of ultrasound stimulation.
Dr. Xian has served as the first author and co-first author of publications in prestigious journals such as PNAS, Advanced Science, and Cell Reports. Additionally, her work has received recognition at major international conferences, where it has been selected for oral presentations and has earned multiple Best Presentation awards, including at the 11th WACBE World Congress on Bioengineering 2024, the 1st Asia-Pacific Neuroscience Student Congress, the HKSAN 2nd Annual Conference 2021, and the 2nd FUN Symposium 2021.
Academic and Professional Experience
- Research Assistant Professor, Department of Biomedical Engineering, The Hong Kong Polytechnic University, 11/2024–Current
- Postdoctoral Fellow, Department of Biomedical Engineering, The Hong Kong Polytechnic University, 2021–2023
Research Interests
Research Output
- Xian, Q. *, Qiu, Z. *, Murugappan, S., Kala, S., Wong, K.F., Li, D., Li, G., Jiang, Y., Wu, Y., Su, M. and Hou, X., 2023. Modulation of deep neural circuits with sonogenetics. Proceedings of the National Academy of Sciences, 120(22), p.e2220575120.
- Zhu, J. *, Xian, Q. *, Hou, X. *, Wong, K.F., Zhu, T., Chen, Z., He, D., Kala, S., Murugappan, S., Jing, J. and Wu, Y., 2023. The mechanosensitive ion channel Piezo1 contributes to ultrasound neuromodulation. Proceedings of the National Academy of Sciences, 120(18), p.e2300291120. (co-first author)
- Hou, X. *, Qiu, Z. *, Xian, Q. *, Kala, S. *, Jing, J., Wong, K.F., Zhu, J., Guo, J., Zhu, T., Yang, M. and Sun, L., 2021. Precise ultrasound neuromodulation in a deep brain region using nano gas vesicles as actuators. Advanced Science, 8(21), p.2101934. (co-first author)
- Xian, Q.*, Qiu, Z.*, Kala, S.*, Guo, J.*, Zhu, J., Wong, K.F., Guo, S.S.Y., Zhu, T., Hou, X. and Sun, L., 2021. Protocol for the sonogenetic stimulation of mouse brain by non-invasive ultrasound. STAR protocols, 2(2), p.100393.
- Xian, Q.*, Qiu, Z.*, Kala, S., Wong, K.F., Guo, J. and Sun, L., 2021. Behavioral and functional assessment of ultrasound neuromodulation on Caenorhabditis elegans. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 68(6), pp.2150-2154.
- Qiu, Z.*; Kala, S.*; Guo.; J.*; Xian, Q.*; Zhu, J.; Zhu, T.; Hou, X.; Wong, K.; Yang, M.; Wang, H.; Sun, L., Targeted neurostimulation in mouse brains with non-invasive ultrasound. Cell reports, 2020. 32(7): p. 108033. (co-first author)
