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Prof. Michael Yu
PolyU Scholars Hub

Prof. Yu Wing-yiu, Michael

Professor

Education and Academic Qualifications

  • Bachelor of Science, The University of Hong Kong
  • Doctor of Philosophy, The University of Hong Kong

Research Overview

Our group aspires to develop fundamental breakthrough for powering future innovation in green chemical synthesis. My research focuses on: (1) Activation of inert carbon-hydrogen bonds for catalytic cross coupling reactions, and (2) Catalytic
multicomponent coupling for stereoselective synthesis.

Academic and Professional Experience

  • Reviewer for chemistry journals:  Angew. Chem. Int. Ed.; J. Am. Chem. Soc.; Org. Lett.; Org. Biomol. Chem.; Adv. Synth. Catal., and Synlett.

Research Interests

  • Catalysis
  • Organic Synthesis
  • Organometallic Chemistry
  • Enantioselective Reactions

Achievements

  • Croucher Foundation Postdoctoral Fellowship 1993-1996;  
  • Best teaching award in ABCT 2011 
  • ABCT Star Award, PolyU 2014
  • ABCT Star Award, PolyU 2016
  • Asian Core Program Lectureship Award (ICCEOCA-8) 2014 (Japan)
  • Asian Core Program Lectureship Award (ICCEOCA-9) 2015 (Taiwan)
  • Asian Core Program Lectureship Award (ICCEOCA-9) 2015 (China)
  • US Provisional Patent Application (60/563,645), "Supported Ruthenium Nanoparticles as Catalysts for cis-Dihydroxylation and Oxidative Cleavage of Alkenes" Che, C.-M.; Yu, W.-Y; Ho, C.-M. (filed on 20 April 2004)

  1. Lee PY, Liang P, Yu WY. Pd(II)-Catalyzed Direct ortho-C-H Acylation of Aromatic Ketones by Oxidative Decarboxylation of α-Oxocarboxylic Acids. Organic Letters. 2017;19(8):2082-5.
  2. Chan CM, Zhou Z, Yu WY. Rhodium-Catalyzed Oxidative Cycloaddition of N-tert-Butoxycarbonylhydrazones with Alkynes for the Synthesis of Functionalized Pyrroles via C(sp3)–H Bond Functionalization. Advanced Synthesis and Catalysis. 2016;358(24):4067-74.
  3. Lu YS, Yu WY. Cp∗Rh(III)-Catalyzed Cross-Coupling of Alkyltrifluoroborate with α-Diazomalonates for C(sp3)-C(sp3) Bond Formation. Organic Letters. 2016;18(6):1350-3.
  4. Ng FN, Lau YF, Zhou Z, Yu WY. [RhIII(Cp*)]-Catalyzed cascade arylation and chlorination of α-diazocarbonyl compounds with arylboronic acids and n -chlorosuccinimide for facile synthesis of α-aryl-α-chloro carbonyl compounds. Organic Letters. 2015;17(7):1676-9.
  5. Ng FN, Zhou Z, Yu WY. [RhIII(Cp*)]-catalyzed ortho-selective direct C(sp 2)-H bond amidation/amination of benzoic acids by N-chlorocarbamates and N-chloromorpholines. A versatile synthesis of functionalized anthranilic acids. Chemistry - A European Journal. 2014;20(15):4474-80.
  6. Ng KH, Zhou Z, Yu WY. [Cp*RhCl2]2-catalyzed ortho-C-H bond amination of acetophenone o-methyloximes with primary N-chloroalkylamines: Convenient synthesis of N-alkyl-2-acylanilines. Chemical Communications. 2013;49(63):7031-3.
  7. Ng KH, Zhou Z, Yu WY. Rhodium(III)-catalyzed intermolecular direct amination of aromatic C-H bonds with N-chloroamines. Organic Letters. 2012;14(1):272-5.
  8. Chan WW, Lo SF, Zhou Z, Yu WY. Rh-catalyzed intermolecular carbenoid functionalization of aromatic C-H bonds by α-diazomalonates. Journal of the American Chemical Society. 2012;134(33):13565-8.
  9. Ng KH, Ng FN, Yu WY. A convenient synthesis of anthranilic acids by Pd-catalyzed direct intermolecular ortho-C-H amidation of benzoic acids. Chemical Communications. 2012;48(95):11680-2.
  10. Ng KH, Chan ASC, Yu WY. Pd-catalyzed intermolecular ortho-C-H amidation of anilides by N-nosyloxycarbamate. Journal of the American Chemical Society. 2010;132(37):12862-4.

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