Professor Feng YAN’s team has successfully developed an ultrasensitive and portable COVID-19 antibody detection sensor based on organic electrochemical transistor (OECT) technology. Fast and easy-to-use, the sensor is designed for testing the antibody levels of people who have either received vaccination or have been infected with the virus.
The whole detection process, which uses saliva sample instead of only blood, takes less than six minutes and the cost per test is only about HK$10. The antibody detection sensor can test the concentration of antibodies from lower than 10fM to higher than 100nM. The detection limit satisfies the needs of exquisite analytical sensitivity for saliva.
Professor YAN said that since the detection process is non-invasive, self-sampling is highly possible. Moreover, the operation and result reading are very simple with the use of a smartphone, and hence the sensor is suitable for instant detection and large-scale screening scenarios.
The next plan of the research team is to apply for funding for clinical studies in collaboration with different medical and testing institutions. They expect that the novel device can be commercialised as soon as practicable and applied for antibody detection of other viruses.
