Academic Staff
- TU515a
- +852 3400 8819
- guiyi.gong@polyu.edu.hk
ORCID ID
SCOPUS IDResearch Overview
Dr. Gong’s research interests center on the pharmacological and toxicological study of a variety of molecules, encompassing emerging environmental toxins, natural products, and bioactive peptides.
Education and Academic Qualifications
- Bachelor of Science in Resources and Development of Traditional Chinese Medicine, China Pharmaceutical University
- Master of Science in Chemistry of Traditional Chinese Medicine, China Pharmaceutical University
- Doctor of Philosophy in Biomedical Sciences, University of Macau
Research Interests
Achievements
- Gong G*, Kam H, et al. 6-Benzylaminopurine causes lipid dyshomeostasis via disruption of glycerophospholipid metabolism in zebrafish [J]. Science of the Total Environment, 2023, 878: 163194.
- Chen, Qian, … Gong G*, et al. A new invertebrate NPY-like polypeptide, ZoaNPY, from the Zoanthus sociatus, as a novel ligand of human NPY Y2 receptor rescues vascular insufficiency via PLC/PKC and Src-FAK-dependent signaling pathways. Pharmacological Research, 2024: 107173.
- Gong G, Kam H, Tse Y, et al. Forchlorfenuron (CPPU) causes disorganization of the cytoskeleton and dysfunction of human umbilical vein endothelial cells, and abnormal vascular development in zebrafish embryos [J]. Environmental Pollution, 2021, 271: 115791.
- Gong G, Kam H, Tse Y, et al. Cardiotoxicity of forchlorfenuron (CPPU) in zebrafish (Danio rerio) and H9c2 cardiomyocytes [J]. Chemosphere, 2019, 235: 153-162.
- Gong G, Chen H, Kam H, et al. In vivo screening of xanthones from Garcinia oligantha identified Oliganthin H as a novel natural inhibitor of convulsant [J]. Journal of Natural Products, 2020, 83(12): 3706–3716.
- Gong G*, Kam H, Tse Y, et al. Role of endocrine disruption in toxicity of 6-benzylaminopurine (6-BA) to early-life stages of zebrafish [J]. Ecotoxicology and Environmental Safety, 2022, 232: 113287.
- Gong G*, et al. 6‐benzylaminopurine causes endothelial dysfunctions to human umbilical vein endothelial cells and exacerbates atorvastatin‐induced cerebral hemorrhage in zebrafish. Environmental Toxicology, 2024, 39(3): 1258-1268.
- Gong G, Jiang L, Lin Q, et al. In vivo toxic effects of 4-methoxy-5-hydroxy-canthin-6-one in zebrafish embryos via copper dyshomeostasis and oxidative stress [J]. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2018, 204: 79-87.
- Gong G, Lin Q, Xu J, et al. In vivo SAR and STR analyses of alkaloids from Picrasma quassioides identify 1-hydroxymethyl-8-hydroxy-β-carboline as a novel natural angiogenesis inhibitor [J]. RSC Advances, 2016, 6(12): 9484-9494.
- Liao Q#, Gong G#, Siu S W I, et al. A Novel ShK-Like Toxic Peptide from the Transcriptome of the Cnidarian Palythoa caribaeorum Displays Neuroprotection and Cardioprotection in Zebrafish [J]. Toxins, 2018, 10(6): 238.
