Academic Staff

PolyU Scholars Hub

Prof. Wong Ka-hing

DoRiFood & Professor

Y809
+852 3400 8864
kahing.wong@polyu.edu.hk

PolyU Scholars Hub

ORCID ID

SCOPUS ID

Research Overview

Our lab is interested in developing natural bio-resources into novel functional foods for prevention and/or treatment of chronic diseases.

Education and Academic Qualifications

Bachelor of Science, The Chinese University of Hong Kong
Master of Philosophy, The Chinese University of Hong Kong
Doctor of Philosophy, The Chinese University of Hong Kong

Academic and Professional Experience

Appointment in Government Department / Professional Organization:

2023-2026 Member, Advisory Council on Food and Environmental Hygiene, Environment and Ecology Bureau, The Government of Hong Kong SAR
2023-2026 Governing Board Member, Hong Kong Organic Resource Centre
2020-2026 Committee Member, Advisory Committee on Sustainable Fisheries Development Fund, Agriculture, Fisheries and Conservation Department, The Government of Hong Kong SAR
2019-2021 Honorary Advisor, Hong Kong Health Food Association
2018-2022 Honorary Advisor, Institution of Dining Art
2018-2024 Committee Member, Expert Committee on Food Safety, Centre for Food Safety, Food and Environmental Health Department, The Government of Hong Kong SAR
2017-2021 Committee Member, Advisory Committee on Agriculture and Fisheries, Agriculture, Fisheries and Conservation Department, The Government of Hong Kong SAR
2016-2020 Admission Panel Member, Technology Business Incubation Programme, Hong Kong Science and Technology Parks Corporation
2016-2022 Mainland Fishermen Deckhands Scheme Appeal Committee Member, Agriculture, Fisheries and Conservation Department, The Government of Hong Kong SAR
2016-2022 Marine Fish Scholarship Fund Advisory Committee Member, Agriculture, Fisheries and Conservation Department, The Government of Hong Kong SAR
2014-2026 Standard Board Member, Hong Kong Organic Resource Centre Certification Ltd.
2014-2025 Technical Expert (Food Category), Hong Kong Q-Mark Council, Federation of Hong Kong Industries
2011-2027 HKCAS Technical Expert, ISO 22000:2005 Food Safety Management System - Hong Kong Accreditation Service, Innovation and Technology Commission, The Government of Hong Kong SAR

Research Interests

Achievements

2023 - Bronze Medal Invention Award, 48th International Exhibition of Inventions of Geneva, Geneva, Switzerland.
2022 - IAAM Fellow and IAAM Scientist Award, International Association of Advanced Materials, Ulrika, Sweden
2021 - 2020年度高等学校科学研究优秀成果奖（科学技术）: 技术发明奖二等奖, 教育部, 中國
2015 - Technology Transfer Award-Merit, Outstanding Professional Services Awards 2014, PolyU, Hong Kong
2014 - Gold Medal Invention Award, 42nd International Exhibition of Inventions of Geneva, Geneva, Switzerland.
2014 - Thailand Award for the Best International Invention, 42nd International Exhibition of Inventions of Geneva, National Research of Thailand, Thailand
2014 - 深圳市科技项目奖, 深圳, 中国
2013 - Material Invention Order of Merit, 2013 Korea Inventor Award Festival, Seoul, Korea.
2013 - Special Gold Medal Award, 2013 World Inventor Award Festival, Seoul, Korea.
2013 - Food and Material Invention Order of Merit, 2013 World Inventor Award Festival, Seoul, Korea.
2012 - Gold Medal Invention Award, 40th International Exhibition of Inventions of Geneva, Geneva, Switzerland.
2012 - Prize of the Chinese Delegation of the Exhibition, 40th International Exhibition of Inventions of Geneva, China Patent Information Center of SIPO, PRC
2011 - Winner of Young Investigator Award, 2011 International Conference on Food Factors, Taipei, Taiwan

黄家兴、曾超华、余嘉明、陈霭仪. 含茶叶渣的复合3D打印材料及其制备方法与应用. 2022.11. 中国, CN202211488554.1
黄家兴、董晓莉、都中蕊. 功能化纳米硒水溶胶及其治疗神经退行性疾病的应用. 2022.08. 中国, CN202211032665.1
黄家兴、董晓莉、陆家谦. 一种功能化纳米硒水溶胶于抗肿瘤方面的应用. 2022.06. 中国, CN202210637693.X.
黄家兴、董晓莉、陆家谦、张兆滔. 一种纳米硒水溶胶及其制备方法与应用. 2019.12, 中国, ZL201911215358.5.
夏凡、郭颖轩、黄家兴、陆家谦、张兆滔. 有免疫增强功效的壳聚糖纳米硒水溶胶及制备、保存和应用, 2019.01, 中国, ZL201910027253.0.
黄家兴、陈填烽. 有抗肿瘤活性的纳米硒水溶胶及制备、保存方法和应用, 2016.02, 中国，ZL201610086666.2
Tianfeng Chen, Kahing Wong, Hualian Wu, Wenjie Zheng, Man Kin Wong, Wing Yin Cornelia Man. Pleurotus tuber-regium polysaccharide functionalized nano-selenium hydrosol with anti-tumor activity and preparation method thereof. 2015.07, USA, US9,072,669B2.
陈填烽、黄家兴、吴华莲、郑文杰、黄文健、文咏贤. 具有抗肿瘤活性的虎奶菇多糖功能化纳米硒水溶胶及其制备方法, 2011.07, 中国, CN201110208539.
相大鹏、黄文健、刘青、韦晓群、黄家兴、黄茳钒、邵仕萍. 一种基于金属催化偶联反应的食品中甲醛的检测方法及其试剂盒, 2014.08, 中国，ZL201410409453.X.
陈填烽、郑文杰、蒋洁、杨芳、黄家兴.同时分离高纯度的藻蓝蛋白和别藻蓝蛋白的方法与应用, 2011.9, 中国, ZL201110268917.

Wu J, Zou S, Gong Y, Li X, Wu Y, Wu J, Wong KH (2024). Functionalized selenium nanoparticles ameliorated acetaminophen-induced hepatotoxicity through synergistically triggering PKCδ/Nrf2 signaling pathway and inhibiting CYP 2E1. Food Sci Hum Wellness 13, 932-945.
Luk KH, Chan CH, Liu ZW, Jiao CW, Yang XB, Dong XL, Wong KH (2023). Selenium nanoparticles functionalized by mushroom polysaccharide-protein complex: A novel nano-mineral for managing postmenopausal osteoporosis. J Funct Foods 110, 105832.
Liu J, Lia W, Lin Y, Peng Y, Zhan M, Lai H, Chang Y, Li Y, Wong KH, Chen B, Chen T (2023). Tumor microenvironment-responsive metal nanotherapeutics for breast cancer chemo-/immunotherapy. NPG Asia Materials 15, 26.
Xia IF, Kong HK, Wu MMH, Lu Y, Wong KH, Kwok KWH (2022). Selenium nanoparticles (SeNPs) immunomodulation is more than redox improvement: Serum proteomics and transcriptomic analyses. Antioxidants 11, 964.
Zhang Z, Du Y, Liu T, Wong KH, Chen T (2019). Systematic acute and subchronic toxicity evaluation of polysaccharide-protein complexes-functionalized selenium nanoparticles with anticancer potency. Biomater Sci 7, 5112-5123
Zhao J, Luk KH, Cheung ST, Wong KH, Chen T (2019). Potentiation of in vivo anticancer efficacy of selenium nanoparticles by mushroom polysaccharides surface decoration. J Agric Food Chem 67, 2865–2876.
Mei C, Wang N, Zhu X, Wong KH, Chen T (2018). Photothermal-controlled nanotubes with surface charge flipping ability for precise synergistic therapy of triple-negative breast cancer. Adv Funct Mater
Huang G, Liu Z, He L, Luk KH, Cheung ST, Wong KH, Chen T (2018). Autophagy is an important action mode for functionalized selenium nanoparticles to exhibit anti-colorectal cancer activity. Biomater Sci 6, 2508-2517.
Yu S, Luk KH, Cheung ST, Kwok, KWH, Wong KH, Chen T (2018). Polysaccharide-protein complex-decorated selenium nanosystem as efficient bone-formation therapeutics. J Mater Chem B 6, 5215-5219.
Nie T, Wu H, Wong KH, Chen T (2016). Facial synthesis of highly uniform selenium nanoparticles using glucose as reductant and surface decorator to induce cancer cell apoptosis. J Mater Chem B, 4, 2351-2358.
Wang Y, Li W, Yang Y, Zeng Q, Wong KH, Li X, Chen T (2015). An integrin-targeting nanosystem as the carrier of selenadiazole derivative to induce ROS-mediated apoptosis in bladder cancer cells, from rational design to action mechanisms. J Mater Chem B, 3, 9374-9382.
Yip J, Liu L, Wong KH, Leung PHM, Yuen MCW, Cheung MC (2014). Investigation of antifungal and antibacterial effects of fabric padded with highly stable selenium nanoparticles. J Appl Polym Sci, 131, 8886-8893.
Wu H, Zhu H, Li X, Liu Z, Zheng W, Chen T, Yu B, Wong KH (2013). Induction of apoptosis and cell cycle arrest in A549 human lung adenocarcinoma cells by surface-capping selenium nanoparticles: an effect enhanced by polysaccharides-protein complexes from Polyporus rhinocerus. J Agric Food Chem, 61, 9859-9866.
Wu H, Li X, Liu W, Chen T, Li Y, Zheng W, Man C, Wong MK, Wong KH (2012). Surface decoration of selenium nanoparticles by mushroom polysaccharide-protein complexes to achieve enhanced cellular uptake and anti-proliferative activity. J Mater Chem 22, 9602-9610.

Wong KH, Cheung PCK (2008). Sclerotia: Emerging functional food derived from mushrooms. In: Mushrooms As Functional Foods. PCK Cheung (ed.). NJ, USA: John Wiley & Sons, Inc. pp.111-146.