Academic Staff
- Y817-03
- +852 3400 8668
- xiaoli.dong@polyu.edu.hk
ORCID ID
SCOPUS IDBiography
My research interests include Pathogenic mechanism studies of age-related diseases including Parkinson's disease and osteoporosis, Novel therapy (Food-based therapies) development for treatment of neurodegenerative disease and bone disease and Functional food development for mental and bone health.
Research Overview
My research interests include pathogenic mechanism studies of neurodegenerative diseases (Parkinson’s disease in particular); novel therapy (especially food-based therapies) development for treatment of neurodegenerative diseases and medicinal/functional food development for mental health.
Education and Academic Qualifications
- Bachelor of Medicine, Jining Medical College
- Master of Medicine, Qingdao University Medical College
- Doctor of Philosophy, The Hong Kong Polytechnic University
Research Interests
Achievements
- 黄家兴，董晓莉，都中蕊，刘鑫。功能化纳米硒水溶胶及其治疗神经退行性疾病的应用。中国专利，申请号：202211032665.1
- 黄家兴，董晓莉，陆家谦。一种功能化纳米硒水溶胶于抗肿瘤方面的应用。中国专利，申请号：202210637693.X
- 黄家兴，董晓莉，陆家谦，张兆滔。一种纳米硒水溶胶及其制备方法与应用。中国专利，已授权，专利号：ZL 2019 1 1215358.5
- 黄文秀，董晓莉，于文轩。维生素D补充制剂及其应用。中国专利，已授权，专利号：ZL 2019 1 0764988.1
- 黄文秀，董晓莉，曹思思，王奕。齐敦果酸和熊果酸在制备调节维生素D3代谢酶活性的药物中的应用。中国专利，已授权 专利号：ZL 2017 1 1061004.0
- 黄文秀，姚新生，邱佐成，董晓莉，戴毅。异戊烯基二氢黄酮类化合物在防治骨疾病领域的应用 中国专利，已授权 专利号：ZL 2016 1 0102211.5
- 李小花，董晓莉，赵清，张焕。三萜类化合物在制备治疗帕金森药物中的应用。中国专利，已授权 专利号：ZL 2015 1 0673284.5
- Li YH, Jiang ZX, Xu Q, Jin TT, Huang JF, Luan X, Li C, Chen XY, Wong KH*, Dong XL*, Sun XR*. Inhibition of calcium-sensing receptor by its antagonist promotes gastrointestinal motility in a Parkinson’s disease mouse model. Biomedicine & Pharmacotherapy, 2024, 174, 116518 (IF: 7.5; JCR Q1)
- Cao X, Du ZR, Liu X, Wang X, Li C, Zhou SN, Liu JR, Xu PY, Ye JL, Zhao Q, Zhao F, Wong KH*, Dong XL*. Low and high doses of oral maslinic acid protect against Parkinson’s disease via distinct gut microbiota-related mechanisms. Biomedicine & Pharmacotherapy, 2023, 165, 115100. (IF: 7.5; JCR Q1)
- Sun CC, Du ZR, Liu X, Yang Y, Zhou SN, Li C, Cao X, Zhao Q, Wong KH, Chen WF*, Dong XL*. Selenium forms and dosages determined their biological actions in mouse models of Parkinson’s Disease. Nutrients, 2023, 15: 11 (IF: 5.9; JCR Q1)
- Liu X, Du ZR, Wang X, Sun XR, Zhao Q, Zhao F, Wong WT, Wong KH*, Dong XL*. Polymannuronic acid prebiotic plus Lacticaseibacillus rhamnosus GG probiotic as a novel synbiotic promoted their separate neuroprotection against Parkinson’s disease. Food Research International, 2022, 155: 111067 (IF: 8.1; JCR Q1)
- Du ZR, Wang X, Cao X, Liu X, Zhou SN, Zhang H, Yang RL, Wong KH, Tang QJ*, Dong XL*. Alginate and its two components acted differently against dopaminergic neuronal loss in Parkinson's Disease mice model. Molecular Nutrition & Food Research, 2022, 66(2): e2100739 (IF: 5.2; JCR Q1)
- Liu X, Du ZR, Wang X, Luk KH, Chan CH, Cao X, Zhao Q, Zhao F, Wong WT, Wong KH*, Dong XL*. Colonic dopaminergic neurons changed reversely with those in the midbrain via gut microbiota-mediated autophagy in a chronic Parkinson’s disease mice model. Frontiers in Aging Neuroscience, 2021, 13: 649627 (IF: 4.8; JCR Q2)
- Dong XL, Wang X, Liu F, Liu X, Du ZR, Li RW, Xue CH, Wong KH, Wong WT, Zhao Q, Tang QJ. Polymannuronic acid prevents dopaminergic neuronal loss via brain-gut-microbiota axis in Parkinson’s disease model. International Journal of Biological Macromolecules, 2020, 164: 994-1005 (IF: 8.2; JCR Q1)
