JASCO J-1500 Circular Dichroism Spectrometer

Introduction:

Circular Dichroism (CD) is a critical analytical technique that is used to analyze chirality in molecules based on their optical activity. This method measures the difference in the absorption of left and right circularly polarized light in optically active substances.

The J-1500 Series Circular Dichroism spectrophotometers are specifically designed for high-sensitivity measurements in the UV/Visible/NIR regions. These instruments are crucial for laboratory research in areas including biology, chemistry, materials science, and medicine, among others, to characterize the structural characteristics of chiral molecules.

With its advanced capabilities, the J-1500 Series Circular Dichroism spectrophotometers are widely used in protein conformational studies, protein folding studies, DNA/RNA interactions, enzyme kinetics, formulation studies, purity testing of optically active substances, quantitative analysis of pharmaceuticals, natural products chemistry, and much more.

At our laboratory, we utilize the J-1500 Series Circular Dichroism spectrophotometers to conduct cutting-edge research in various fields. We believe that these instruments are essential for any researcher working in the areas of life sciences and material sciences.

Specifications:

Light source: 150 W air-cooled Xenon lamp

Detector: Head-on photomultiplier tube PMT/InGaAs

Modulator: Photoelastic modulator

Measurement wavelength range:

• 163 to 950 nm (PMTdetector)

• 800 to 1600 nm (InGaAs detector)

Spectral bandwidth: 0.01 to 16 nm

Slit width: 1 to 4000 µm

Digital Integration Time (D.I.T.): 0.1 msec to 30 sec.

Scanning mode: Continuous scan /Step scan/Auto response(D.I.T) scan

Scanning speed: up to 10000 nm/min

Photometric Mode: CD, LD, Absorbance, HT voltage, etc.

CD resolution: 0.00001 mdeg

RMS noise:

• 0.004 mdeg (185 nm, 150 W light source)

• 0.003 mdeg (185 nm, 450 W light source)

• 0.007 mdeg (200 nm, 150/450 W light source)

• 0.007 mdeg (500 nm, 150/450 W light source)

Baseline stability: 0.02 mdeg/hr

LD measurement: Full scale 1ΔOD, Resolution 0.000001ΔOD

Photometric range: 0 to 5 Abs

External input terminal: Two channels

Mercury lamp: Used for the instrument inspection

Shutter: Located the light source unit

Sample chamber: 150 mm wide 310 mm deep 165 mm high; Exists the water inlet/outlet ports

Nitrogen gas purging: Atmosphere in the light source unit, monochromator unit, and sample chamber can be purged using dry nitrogen gas. 2L/Min (more than 185nm)

Dimensions: 1055 mm wide 545 mm deep 390 mm high (150 W light source)

Consumables:

• Rectangular quartz cell with teflon cap pathlength:
  • 1 mm and 10 mm